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Dictionary of molecular biology
1 2 4 7 9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

(= suppressor of cytokine signalling)
Family of proteins (SOCS 1-3 and CIS; 211 amino acids) rapidly induced in response to IL-6 and other cytokines, thought to act as negative feedback regulator of JAKs in the intracellular signalling pathway. All contain a central SH2domain. Similar, possibly identical, to JAB and SSI-1.

Оригинал статьи '1.332SOCS' на сайте Словари и Энциклопедии на Академике